They say beauty

They say beauty comes from within—and several companies are putting that theory to the test, offering pills and drinks that promise gorgeous hair, skin, and nails. Six testers, plus nutritionist Susan Kraus, M. S., R. D., of Hackensack University Medical Center and Beverly Hills dermatologist Ava Shamban, M. D., see if they live up to the hype.
A study was recently published online in the journal Circulation, the journal of the American Heart Association, showing that optimistic women are less likely to suffer from, or die of, heart disease. The study is actually really fascinating (the article abstract and the downloadable entire article can be found here.)

I think this particular study highlights some important points:

1. The study participants are very much like the group that we are trying to collect through the Illinois Women’s Health Registry (if you’re an Illinois resident, go join!). They were women in the government-funded Women’s Health Initiative, and the sheer number and racial diversity of participants allowed researchers to make new connections, simply by following the women’s health progress for a couple of years and administering very short questionnaires. It’s amazing what we can do when we all participate in these kind of registries!

2. I think the connection between mental well-being and physical health is really starting to become a key research topic and is likely changing the way patients are treated. As an admitted pessimistic cynic, I really do understand that those stress headaches and upset stomachs are taking their toll, and can be largely under my control. That’s pretty empowering, even for a pessimist.

3. It’s a great example of the benefits of studying several groups of people in scientific studies. The researchers found several statistical differences between the white and black women studied (the disparity in health outcomes between optimists and pessimists was much more striking in the black women studied, for example.) These differences would have been missed if men or white women were allowed to portray some standard of the everyperson.

So go read up! The questions used to classify a person as optimistic or hostile and cynical are particularly amusing, such as having to answer true or false to “ I have often had to take orders from someone who did not know as much as I did,” or “It is safer to trust nobody.” I know I’ll be thinking twice about those negative thoughts about my higher-ups!
Uterine cancer is the most common gynecologic malignancy in the United States. It commonly presents as postmenopausal bleeding (vaginal bleeding/spotting that occurs after menstrual periods had previously stopped for over one year).

Endometrial BiopsyThe clinical approach to postmenopausal bleeding requires a prompt and efficient evaluation to diagnose or exclude cancer. The American College of Obstetrics & Gynecology recently updated their triage recommendations for postmenopausal bleeding. While the initial evaluation may include either endometrial biopsy (a small tissue sample from the inside lining of the uterus) or transvaginal ultrasound, the later has the advantage of being non invasive and consequently painless. If the transvaginal (not abdominal) ultrasound clearly demonstrates the endometrium is ≤ 4mm thick then it excludes uterine cancer with an accuracy of 99%—superior to endometrial biopsy. If it is thicker than this or cannot be clearly seen then further evaluation is warranted. For instance, we can enhance the ultrasound by performing a saline infused sonogram that more accurately reveals small polyps projecting into the uterine cavity, which may be the source of bleeding. Finally, if endometrial thickening is present and cannot be explained by these imaging studies, then an endometrial biopsy is performed in the office.
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